3,5-Dichlorobenzoyl Chloride

Tsarin kwayoyin halitta: Saukewa: C7H3Cl3O
Nauyin Kwayoyin Halitta: 209.46

3,5-Dichlorobenzoyl chloride shine muhimmin tsaka-tsaki na magungunan kashe qwari, magani da rini. A cikin samar da magungunan kashe qwari, ana iya shirya magungunan kashe qwari ta hanyar amsawar benzoic acid; A fagen magani, ana iya shirya magungunan ciwon kai da magungunan hormone antidiuretic. Yana da mahimmancin tsaka-tsaki don haɗin magungunan magungunan kashe qwari pentoxachlor kuma ana amfani dashi sosai a fagen magungunan kashe qwari, magani, kayan aikin hoto da sauransu.
3,5-Dichlorobenzoyl chloride shine matsakaici mai amfani don haɓakar kwayoyin halitta da sauran hanyoyin magunguna. An yi amfani da 3,5-Dichlorobenzoyl chloride a cikin shirye-shiryen:

N- (1,1-dimethylpropynyl) -3,5-dichlorobenzamide, herbicide
(3,5-dichlorophenyl) (2- (4-methoxyphenyl) -5-methylbenzofuran-3-yl) methanone.

3,5-Dichlorobenzoyl chloride shine mahimmancin tsaka-tsaki don haɗin fenpropargyl, wanda aka yi amfani da shi sosai a cikin magungunan kashe qwari, magani, kayan aikin hotuna da sauran filayen.

3,5-Dichlorobenzoyl chloride is obtained by reacting by aryl carboxylic acid with DMF. Dissolve aryl carboxylic acid (10.0 mmol) in 50 mL DCM with drops of DMF to a 100 mL roundbottomed flask. Cool the mixture to 0°C. Add oxalyl chloride (20.0 mmol, 2.0 equivalents) dropwise to the reaction mixture. Allow the reaction mixture to react for another 4 hours. Concentrate the solvent in vacuo. Use the remaining residue directly.