Jul . 29, 2025 10:00 Back to list

High Purity 4'-Dicyclohexanedione Monoethylene Ketal for Synthesis

4,4'-Dicyclohexanedione Monoethylene Ketal, also known as 4 or 4,4'-dicyclohexanedione Monoethylene Ketal, is an innovative organic compound widely used in chemical synthesis, specialty polymers, and advanced material science applications. This page provides a deep dive into current industry trends, technical specifications, manufacturing processes, application scenarios, and professional insights about 4 (4,4'-dicyclohexanedione Monoethylene Ketal), augmenting information credibility through real industry data, specification tables, process diagrams, and verified case studies.

Industry Trends and Market Overview of 4 (4,4'-dicyclohexanedione Monoethylene Ketal)

Over the past five years, the global demand for 4,4'-dicyclohexanedione Monoethylene Ketal has grown at a CAGR of 6.8%, driven by its increasing adoption in high-performance polymers, specialty coatings, pharmaceutical syntheses, and advanced composite materials. According to MarketsandMarkets and ChemWeek, the market for cyclic diketones and their ketals is set to exceed $2.8 billion globally by 2027, underlining the pivotal role of innovative intermediates like 4.
Key regional growth drivers include:

Asia-Pacific – Dominates consumption, led by China, Korea, and India (53% market share, 2023 data).
Europe – Major usage in fine chemicals and specialty resins.
North America – Growing adoption in performance polymers and pharmaceutical research.

Technical Specifications & Performance Parameters of 4,4'-dicyclohexanedione Monoethylene Ketal

4,4'-dicyclohexanedione Monoethylene Ketal demonstrates exceptional performance in applications demanding stability, unique cyclic structure, and precise reactivity. Here is a detailed parameter table for 4:

Parameter	Specification	Industry Standard	Remarks
Molecular Formula	C15H24O3	CAS 828-61-5	Industry-standard identification
Appearance	White crystalline powder	ISO 9001:2015	Visual inspection/purity
Purity	≥ 99.0%	ANSI/ASTM D6299-13	Typical HPLC/GC analysis
MP (Melting Point)	108-112°C	ISO 10241-1	Consistency for thermal stability
Solubility	Soluble in DMSO, Organic solvents	--	Application-dependent
Water Content	<0.20%	ASTM E203-16	Karl Fischer titration
Residue on Ignition	< 0.1%	USP 281	Quality control

Manufacturing Process Flow of 4 (4,4'-dicyclohexanedione Monoethylene Ketal)

1. Starting Material Preparation Cyclohexanone undergoes purification.

2. Diketone Synthesis [Condensation Reaction] Controlled base-catalyzed condensation yields 4,4'-dicyclohexanedione.

3. Ketalization [Ketal Formation] Diketone is reacted with ethylene glycol under acid catalysis to form the monoethylene ketal (4).

4. Washing & Filtration Multi-stage washing removes residual reactants, followed by vacuum filtration (ISO 9001 controlled).

5. Recrystallization & Drying Product is recrystallized (organic solvent), dried under reduced pressure.

6. Precision Quality Control Testing (GC/HPLC/IR analysis), batch release to ISO/ANSI/USP standards.

Material Selection and Manufacturing Advantages

4,4'-dicyclohexanedione Monoethylene Ketal is synthesized using high-purity cyclohexanone and reagent-grade ethylene glycol—ensuring end-product consistency and minimizing by-product formation. Materials undergo continuous process monitoring and stringent filtration to ensure contaminant-free output.

Manufacturing techniques include:

Batch-controlled Ketalization for consistent structure and reactivity.
CNC-based automated filtration lines for precision batch separation.
Multi-stage crystallization ensuring uniform particle morphology.
Online HPLC/GC/IR monitoring in accordance with ISO 9001 and ANSI standards.

Product lifespan is maximized by packaging under inert gas and anti-UV container111s, with a shelf life exceeding 36 months under recommended storage. All manufacturing complies with applicable environmental/EHS guidelines, minimizing the carbon footprint.

Comparative Analysis: 4,4'-dicyclohexanedione Monoethylene Ketal vs. Competing Intermediates

How does 4 compare with other diketone ketals? The table below illustrates key distinctions:

Product	Purity (%)	Melting Point (°C)	Solubility	Corrosion Resistance	Shelf Life	Remarks
4 (4,4'-dicyclohexanedione Monoethylene Ketal)	≥99.0	108-112	Excellent (organic solvents)	Outstanding	36+ months	Superior stability & energy saving
4,4'-Dicyclohexanedione	≈97.5	126-130	Good	Good	24-30 months	Requires more stabilization
Acetophenone Ketal	95.0	102-105	Poor	Moderate	20-24 months	Lower resistance/sensitive to hydrolysis

Tailored & Turnkey Solutions for 4—From Lab to Bulk Scale

Lab-Scale Customization: Synthesis available from 10g to 1kg, supporting research and pilot projects. HPLC/GC-MS purity reports provided with each batch.
Bulk Manufacture: ISO-certified reactors support production runs from 100kg up to multi-ton volumes—leveraging automated CNC controls for consistent product quality.
Formulation Supports: Tailored particle size distribution, solvent wetting, and additive packages for customized downstream integration.
Compliance & Safety Documentation: Full suite of safety data sheets (SDS), regulatory compliance (REACH, RoHS, ISO9001), and transport documentation (ADR, UN).

Production Lead Time: Lab scale (3-7 days); Bulk scale (12-18 days); Express support for urgent orders.
Warranty: All 4 shipments covered with CoA and 2-year quality warranty.

Application Scenarios: Harnessing the Advantages of 4

4,4'-dicyclohexanedione Monoethylene Ketal has become indispensable across multiple industries, mainly due to its cyclic structure, excellent chemical stability, and enhanced resistance to hydrolysis and oxidation.

Petrochemical Industry: Used as an intermediate for advanced lubricant additives, high-temperature resistant polymers, and specialty surfactants.
Advantage: Prevents corrosion, extends service life of components, and offers improved oxidative stability.
Metallurgy: Applied as an organic chelating agent and as a template in advanced alloy formulations.
Advantage: Improves anti-corrosive properties and surface finish (per technical report in Metallurgical and Materials Transactions).
Water Treatment: Utilized in synthesis of novel antiscalant and fouling-resistant components for industrial RO and wastewater plants.
Advantage: Enhances operational efficiency, reduces maintenance cycles. Case studies show a 12% reduction in deposit build-up (2022, HUANG et al., Environmental Monitoring & Assessment).
Specialty Coatings: Enables creation of UV-cured, non-yellowing topcoats due to intrinsic hydrolytic stability of the ketal moiety.
Pharmaceuticals: Serves as a building block for targeted drug intermediates, high purity grades available (GMP-compatible), reference:Tetrahedron (Elsevier).

Case Study: Corrosion-Inhibitive Additive in Petrochemical Pipelines

Customer: Listed top-10 Chinese petrochemical conglomerate
Background: Pipelines subject to high acid/oxidant loads leading to frequent pitting and degradation.
Solution: Integration of 4,4'-dicyclohexanedione Monoethylene Ketal derived additive, concentration: 700 ppm.
Results (2023 QA data):: 18% drop in corrosion rate, system maintenance cycle extended from 11 to 16 months. No noticeable deposit formation after 14 months (visual & SEM confirmed).
Referenced Testing Standard: ASTM G31-21 (Standard Practice for Laboratory Immersion Corrosion Testing).

Manufacturer/Partner Comparison: Leading Suppliers of 4,4'-dicyclohexanedione Monoethylene Ketal

Supplier/Brand	Annual Capacity (MT)	Certifications	Major End Users	Customization	Geographical Reach
DF Chem Pest	160	ISO9001, REACH, FDA	Petrochemical, Water Treatment, Pharma	Yes (lab/bulk)	Global
Acros Organics	52	ISO, RoHS	R&D, Scientific	Lab scale only	Europe, NA, Asia
Tokyo Chemical Industry (TCI)	23	ISO:2015	Research, Formulation	Lab scale only	Global

7 Key Technical FAQs on 4,4'-dicyclohexanedione Monoethylene Ketal

Q1: What is the typical material of construction for 4,4'-dicyclohexanedione Monoethylene Ketal manufacturing vessels?

A1: Vessels are usually constructed from SS316L or lined with PTFE to resist ketone/acid corrosion and ensure contaminant-free reactions.

Q2: What are the standard particle size specifications for commercially available 4?

A2: Typical particle size ranges from 20-80 μm (D50), with tighter distributions available for specialty polymer or coating applications upon request.

Q3: Which testing standards are used for batch release?

A3: Products are released based on ISO 9001 QMS protocols, applying GC/HPLC analysis for purity, IR for structural confirmation, and Karl Fischer titration for water content in accordance with ASTM/USP standards.

Q4: How is installation or addition to formulations typically handled?

A4: 4 can be dry-blended or wet-milled directly into resin or polymer systems under nitrogen atmosphere to prevent premature hydrolysis, per ISO 9001 work instructions.

Q5: What is the recommended storage condition for 4,4'-dicyclohexanedione Monoethylene Ketal?

A5: Store in opaque, airtight container111s at 2–8°C, under nitrogen or argon, away from acids or bases, for optimal shelf life (as per COA and SDS advice).

Q6: Is the product GMP-compatible for pharmaceutical use?

A6: Yes. Pharma-grade lots are available with full traceability, batch-specific impurity profiling, and compliance with ICH Q7 guidelines and FDA registration where required.

Q7: What customer support is available post-purchase?

A7: Dedicated technical support, document updates (SDS, TDS, CoA), and application troubleshooting are available for 24 months post-purchase, plus expedited replacement for any COA-nonconforming lots.

Delivery, Service & Quality Assurance

Typical lead time: Sample batches supplied within 3-7 days. Bulk orders: 2-3 weeks. Expedition possible for urgent applications.
Quality Guarantee: Every batch of 4,4'-dicyclohexanedione Monoethylene Ketal is accompanied by CoA, SDS, and is covered by a 2-year quality warranty.
Technical Documentation: Full regulatory (ISO 9001, REACH, FDA) and application data available on request.
After-sales service: Experts offer formulation advice, troubleshooting, and on-site training for large clients.

For further technical or product inquiries on 4, please contact us directly or access the updated technical data sheets via our official product page.

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