Jul . 28, 2025 04:01 Back to list

Prothioconazole Fungicide – Advanced Crop Protection Solutions

As prothioconazole continues to redefine standards in crop protection, its innovative chemistry, proven efficacy, and rapid adoption have made it a cornerstone fungicide in global agri-industries. This article delves into the latest trends, manufacturing technology, rigorous standards compliance, and real-world case studies of prothioconazole and its combinations, providing a comprehensive resource for professionals seeking excellence in disease management.

Figure 1: prothioconazole fungicide field application in wheat

1. Industry Trends & Market Dynamics of Prothioconazole Fungicide

Prothioconazole, a triazolinthione fungicide, has witnessed exponential demand across cereal, oilseed, and specialty crop markets from 2019 onward. According to IHS Markit, the global prothioconazole fungicide segment grew at a CAGR of 8.5% (2019-2023), underpinned by its robust efficacy against key pathogens such as Fusarium, Septoria, and Ramularia.

The combination products, such as prothioconazole trifloxystrobin, extend efficacy spectrum, delivering multisite protection and resistance management. Regulatory bodies, including the EPA, EFSA, and China's Ministry of Agriculture, recognize prothioconazole products as essential tools compliant with international MRLs and eco-toxicological standards.

Key Market Indicators (2024):

Market Share: Prothioconazole-based products account for 18% of azole fungicide global sales (Source: Phillips McDougall, 2024)
Industry Adoption: 79 countries registered prothioconazole and/or its mixtures in national plant protection programs.
New Formulations: Sustainable, low-drift, and tank-mix-ready prothioconazole products are in rapid development.

2. Product Specification & Parameters: Prothioconazole Products Overview

    
      Prothioconazole (C14H15Cl2N3OS) is an advanced DMI fungicide (Demethylation Inhibitor) with high systemicity, enabling superior crop protection through preventive, translaminar, and curative action.

Parameter	Value / Range	Significance
CAS No.	178928-70-6	Global chemical traceability
Formulation Types	EC 250 g/L, SC 250-300 g/L, WG, mixtures (trifloxystrobin, tebuconazole)	Flexibility to agronomic needs
Purity	>98.5% (technical), 25-40% (formulated)	Ensures high efficacy and minimal residues
pH Stability	4~8	Stable across standard agricultural tank mixes
Molecular Weight	378.3	Relevant for formulation and application
WHO Class	III (Slightly Hazardous)	Improved operator safety
Residual Activity	Up to 3-4 weeks in field conditions	Extended crop protection window
Storage Conditions	Dry, cool, ventilated; 2-3 years shelf life	Quality assurance for distributors/farmers

Figure 2: prothioconazole products manufacturing facility (ISO 9001 certified)

3. Prothioconazole Manufacturing Process: From Raw Material to Finished Fungicide

Process at a Glance: Raw material procurement → precision reaction and synthesis → advanced CNC purification → automated formulation blending → multi-stage ISO/ANSI/FDA quality control
Learn more about Prothioconazole Production Process ▶

Step 1: Material Selection — Adopt high-purity dichloro-thiophenol, propenyl intermediates, and pharmaceutical-grade solvents to ensure chemistry integrity.
Step 2: Synthesis & Reaction Control — Precision-controlled batch reactors, monitored by in-line sensors, yield optimal conversion rates (≥95%).
Step 3: CNC Purification — Automated centrifugation and filtration guarantee sub-micron particulate elimination, critical for EC/SC stability.
Step 4: Formulation Blending — PLC/SCADA-driven lines for exact mixing with co-formulants (trifloxystrobin, surfactants) for robust prothioconazole trifloxystrobin products.
Step 5: Quality Control — LC-MS/MS, FTIR, and UV spectroscopy employed per ISO 9001:2015, FAO/WHO specifications. All lots possess full batch traceability and are subjected to storage simulation (40°C/6 months) to test product longevity.
Step 6: Packaging & Logistics — UN-approved HDPE, aluminum foil lining, and tamper-evident seals for safe global transit.

Technical Specifications Table (2024 Batch Sample)

Criteria	Prothioconazole Technical	Prothioconazole 250SC	Prothioconazole Trifloxystrobin 325SC
Active Content (%)	≥98.8	25.0±0.3	Pro: 12.5, Tri: 32.5
Appearance	Off-white crystalline powder	Milky white liquid	Pale yellow suspension
Water Content (%)	≤0.5	≤0.75	≤0.8
pH (1% soln)	6.7	6-8	6-7.5
Suspensibility (%)	-	≥97	≥95
Compatibility (Tank Mix)	Good	Excellent	Excellent
ISO/ANSI Compliance	ISO 9001, FAO, ANSI Z400.1	ISO 9001, FAO	ISO 9001, FAO, ANSI/NSF

4. Application Scenarios: Where Prothioconazole Fungicide Excels

Cereals (Wheat, Barley): Leading global fungicide for Fusarium head blight, Septoria, rusts. Field trials (Bayer CropScience 2023) show a 47% yield loss reduction versus untreated, outperforming traditional tebuconazole by 7-12%.
Oilseeds (Rapeseed, Canola): Effective against Sclerotinia stem rot, Alternaria; extended residual protection ensures pod integrity at harvest.
Soybeans, Corn: Combined prothioconazole trifloxystrobin products provide broad-spectrum coverage and maximize resistance management.
Turf & Ornamentals: Low phytotoxicity and excellent rainfastness make it ideal for golf courses and high-value landscapes.

Key Advantages in Application:

Advanced DMI mode of action (sterol demethylation inhibition, FRAC Group 3)
Systemic & translaminar action—provides true preventive and curative efficacy
Tank-mix flexible with triazoles, strobilurins (e.g., prothioconazole trifloxystrobin), and biological adjuvants
Minimal impact on beneficial microflora and pollinators under recommended rates
Meets global residue tolerance (Codex Alimentarius & EFSA)
Proven cost-per-acre savings versus multi-spray programs

Figure 3: prothioconazole trifloxystrobin application in oilseed crop demonstration plot

5. Prothioconazole: Technical Superiority, Manufacturer Comparison & Customization

Manufacturer	Technical Purity (%)	QA Standard	Main Formulations	Service (Years)	Global Registration
DF Chem Pest (Product Link)	≥98.8	ISO 9001, FAO/WHO	250SC, Trifloxystrobin 325SC, WG	25+	USA, EU, LATAM, APAC, Africa
Bayer CropScience	≥98.5	ISO 9001, EPA, EFSA	Propulse®, Folicur®	100+	All major markets
SYNTECH Agro	≥98.0	ISO 9001, ASEAN	250SC, mixtures	18	SE Asia, MEA, Turkey
UPL Limited	≥97.8	FAO, Indian BIS	SC, WG	34	Asia, Africa, LATAM

DF Chem Pest stands out by offering fully customizable prothioconazole products with tailored co-formulants, packaging aesthetics, and regional labeling approved by multi-national clients (Bunge, COFCO, Yara, Amaggi). The company has invested in integrated R&D labs, pilot trial field stations, and rapid logistics, ensuring late-stage disease rescues or in-season supply chain surges are handled without efficacy compromise.

6. Case Studies & Real-World Feedback: Prothioconazole Application

6.1. Wheat Fusarium Head Blight Control (Canada, 2023)

Situation: Severe wet season, Fusarium pressure exceeding 35% field infection (source: Manitoba Crop Surveillance).
Solution: Split application of prothioconazole 250SC, 0.7 L/ha at flowering + prothioconazole trifloxystrobin 0.6 L/ha at flag leaf.
Effect: Disease index reduced by 89%, DON toxin level cut by 56%, yield gain of 1.8 t/ha (vs. non-treated).
Grower Feedback: “Disease control and grain quality were exceptional, even with late high-pressure infection. Sprayer cleanout and operator safety measures met all regulatory norms.”

6.2. Oilseed Rape (Europe, 2022)

Farm: 380 ha, Germany, Sclerotinia-prone region.
Approach: One-pass prothioconazole trifloxystrobin at early flowering, 0.8 L/ha.
Outcomes: Pod integrity maintained 99%, reduction in sclerotinia lesions by 78%, pod shatter visually reduced.
Operator Notes: “Product exhibited zero phytotoxicity and stuck well after 10mm rainfall event—reapplication not necessary and program cost effective.”

6.3. Custom-Prepared Prothioconazole Product (Australia, 2023)

Customer: Leading contract spray service; required high-suspension concentrate.
Solution: DF Chem Pest developed a 350SC custom blend to suit their unique equipment. Yielded 2 extra tissue-penetrating days compared to market average, with no nozzle blockages reported across 6000 ha.
Feedback: “Being able to specify adjuvant and pH options directly saved us downtime and off-label issues. Technical support highly responsive.”

7. FAQ: Prothioconazole Professional FAQ

Expert Technical FAQ about Prothioconazole Fungicide

Q1: What is the recommended material grade for long-storage prothioconazole formulations?

Prothioconazole technical should be >98.5% purity, synthesized using analytical grade intermediates, free from arylamine or halogen impurities (per ISO 17034 supplier guidelines).

Q2: Does prothioconazole require specific application equipment specifications?

Use flat-fan or low-drift nozzles (ISO/ANSI 19.02), clean sprayer tanks, and ensure agitation for SC/WG. For trifloxystrobin mixtures, check for anti-foam compatibility.

Q3: What are the suspension and wetting standards for prothioconazole SC?

FAO/WHO standard: >95% suspensibility and <0.01% foam in ASTM wetting test. All SCs from DF Chem Pest pass these criteria best-in-class.

Q4: Which industry standards apply to packaging of prothioconazole fungicides?

UN-certified HDPE (Type II), aluminum or polytetrafluoroethylene lining, and tamper-evident closures per ISO 9001 and ANSI.

Q5: What is the default shelf-life and storage requirement?

24-36 months at 2-30°C, dry and sunlight-protected. Store as per GHS/CLP standards for chemical storage.

Q6: How is product traceability ensured?

All batches labeled with unique codes, COA, MSDS, and full supply chain record in compliance with FDA FSMA.

Q7: Are prothioconazole products compatible with biostimulants or micronutrient foliar feeds?

Yes, most prothioconazole SC/WG products tested remain physically compatible with micronutrients/zinc, but always conduct a jar test prior to full tank-mix.

8. Delivery, Warranty & Customer Support

Lead Time: Standard delivery window is 7-15 business days ex-works for prothioconazole products. Express and DDP/DDU service available globally.

Warranty: All shipments covered by a minimum 24-month product integrity warranty. Each lot delivered with full COA, batch traceability, and complies with FAO/WHO/ISO 9001 requirements.

After-Sales Support: Dedicated technical support available via online consultation, field troubleshooting, and annual customer training. Onsite trials and formulation optimization available for large clients.

Digital MSDS/COA/live technical documentation download.
24/7 multilingual customer support team.
ISO-compliant complaint response (within 24h).

9. References & Further Reading

Phillips McDougall. (2024). “World Agrochemical Industry Overview”. iHS Markit Reports
FRAC Mode of Action Classification. Fungicide Activity and Resistance Committee
Codex Alimentarius: International Food Standards. FAO/WHO Codex
Crop Science Forum and Food Security, 2023: “Prothioconazole resistance management strategies” Wiley.com
Agriprofessionals Forum (Field Experiences): The Farming Forum
Bayer Field Trials. (2023). “Prothioconazole efficacy on wheat and OSR”. CropScience.Bayer.com
DF Chem Pest product documentation: Prothioconazole Official

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