Molecular Formula / Molecular Weight |
C3H2F6O = 168.04 |
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Physical State (20 deg.C) |
Liquid |
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Storage Temperature |
Room Temperature (Recommended in a cool and dark place, <15°C) |
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CAS RN |
920-66-1 |
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Melting Point |
-4 °C |
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Boiling Point |
58 °C |
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Specific Gravity (20/20) |
1.62 |
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Refractive Index |
1.28 |
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Maximum Absorption Wavelength |
229 nm |
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Solubility in water |
Soluble |
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Solubility (soluble in) |
Ether, Acetone |
UN Number |
UN1760 |
Class |
8 |
Packing Group |
III |
1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP) is a clear, colorless, oily, combustible liquid. Odor is described as aromatic.
1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP or HFP): A Solvent with Specific Properties. 1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP or HFP) is used as a solvent with specific properties. Its combination of high H bonding donor ability, low nucleophilicity, and high ionizing power allows reactions to proceed under mild conditions, which usually require the use of added reagents or metal catalysts to be carried out. In addition, HFIP is used as acid in volatile buffers for ion pair HPLC.
Hexafluoroisopropanol(1,1,1,3,3,3-Hexafluoro-2-propanol) can be used to prepare a variety of high-end chemicals such as fluorosurfactants, fluorine-containing emulsifiers, fluorine-containing pharmaceuticals, and used as a solvent or cleaning agent for electronics industry.
Hexafluoroisopropanol is used to produce high-end chemicals, such as fluorinated surfactants, fluorinated emulsifier and fluorinated medicine, etc. HFIP is used as a solvent or cleaner in electronic industry.
1,1,1,3,3,3-Hexafluoro-2-propanol effects the native state of proteins, denaturing them as well as stabilizing the α-helical conformation of unfolded proteins and polypeptides. It is used as a polar solvent and exhibits strong hydrogen bonding properties.It dissolves substances that are hydrogen-bond acceptors, such as amides, ethers and a wide range of polymers, including those that are not soluble in the most common organic solvents. Usually used for preparing hexafluoroalcohol-functionalized methacrylate polymers for lithographic/nanopatterning materials.