Spirodiclofen represents a breakthrough in acaricide technology as a selective, non-systemic solution targeting destructive mite populations in agriculture. Developed as part of the novel spirocyclic tetronic acid derivatives, this compound offers unique advantages in resistance management and environmental safety profiles.
Modern agriculture faces unprecedented challenges from acarine pests capable of devastating crop yields worldwide. Spirodiclofen emerged as a scientific response to these challenges - a highly effective acaricide specifically targeting mites at various lifecycle stages. Marketed under formulations like Spirodiclofen 24 SC, this compound belongs to the tetronic acid chemical group and functions as a potent inhibitor of lipid biosynthesis.
The development of spirodiclofen marked a significant advance in integrated pest management strategies. Its unique mode of action disrupts energy metabolism in mites by interfering with acetyl-CoA carboxylase, providing exceptional control against resistant strains that had evolved tolerance to earlier generation acaricides. Regulatory approvals began with EPA registration in the early 2000s, with subsequent adoption across European and Asian markets establishing spirodiclofen insecticide as a cornerstone in modern pest management programs.
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Understanding the technical parameters of spirodiklofen provides essential insights into its field performance and formulation stability:
Parameter | Value | Significance |
---|---|---|
IUPAC Name | 3-(2,4-Dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate | Chemical structure classification |
Molecular Formula | C21H24Cl2O4 | Molecular weight: 411.32 g/mol |
CAS Number | 148477-71-8 | Chemical identifier |
Water Solubility (20°C) | 0.05 mg/L | Explains rainfastness characteristics |
Log Pow | 5.6 | High lipophilicity |
Vapor Pressure | 3.0 × 10-7 Pa (25°C) | Low volatility |
Stability in Water (pH 7) | DT50 = 200 days | Optimal stability at neutral pH |
Field trials conducted on multiple continents demonstrate the exceptional performance of Spirodiclofen 24 SC formulations against primary mite species:
Spirodiclofen Molecular Structure
Agricultural Application of Spirodiclofen
Technical-grade Spirodiclofen Packaging
Spirodiklofen insecticide provides critical protection across numerous crop systems through targeted application methods:
Citrus cultivation benefits significantly from spirodiclofen's efficacy against rust mites (Phyllocoptruta oleivora) and citrus red mites (Panonychus citri). Recommended application rates between 0.02-0.04% concentrate deliver residual protection for 21-28 days post-application. In pome fruit orchards, it controls European red mites (Panonychus ulmi) and two-spotted spider mites (Tetranychus urticae) at critical growth stages without phytotoxic effects on sensitive varieties.
Cotton producers rely on Spirodiclofen 24 SC for spider mite management during boll development phases. Application timing coinciding with early mite colonization prevents economic damage to fiber quality parameters. Research demonstrates 89-95% control efficiency at 250-300 mL/hectare application rates in cotton and soybeans when applied preventatively before population explosions.
Spirodiclofen is a new selective, non systemic acaricide belonging to the chemical group of the spirocyclic tetronic acid derivatives. Manufactured to strict ISO quality standards, our technical-grade material guarantees consistent formulation performance.
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The spirodiclofen insecticide market demonstrates robust growth patterns globally, with expansion projections highlighting key regional developments:
Spirodiclofen adoption continues to increase at approximately 4.2% CAGR globally, driven by three primary factors: expanding registrations in developing agricultural economies, resistance management advantages in perennial crop systems, and formulation advancements improving user safety profiles while maintaining efficacy against challenging mite populations.
Spirodiclofen maintains optimal chemical stability within a pH range of 5.0-7.0. Below pH 4, hydrolysis rates increase significantly, with DT50 decreasing to approximately 48 hours. Always conduct jar compatibility tests before mixing with alkaline formulations.
Suspension Concentrate (SC) formulations like Spirodiclofen 24 SC provide superior foliar retention compared to emulsifiable concentrates. The SC particle size distribution directly influences rainfastness, with D90 particle size ≤15μm demonstrating optimal performance characteristics in replicated trials.
The Insecticide Resistance Action Committee (IRAC) classifies spirodiclofen in Group 23, recommending rotation with compounds from Group 6 (avermectins), Group 10 (clofentezine), and Group 20B (acequinocyl) to maintain long-term efficacy through mode of action diversification.
Standard REI for spirodiklofen formulations is 12 hours for low-concentration applications (≤0.03%), extending to 24 hours for higher-rate applications in enclosed environments. Always consult regional regulatory requirements which may impose additional restrictions.
Biological activity increases within the range of 15-28°C, with optimal performance at 22-26°C. Below 15°C, metabolic activity in target organisms decreases, potentially extending time-to-kill by 25-40% compared to optimal temperature conditions.
Current Codex Alimentarius MRLs for Spirodiclofen are: Citrus fruits (0.8 mg/kg), Pome fruits (0.5 mg/kg), Tomatoes (0.5 mg/kg), and Cotton seed (0.05 mg/kg). Always verify destination market regulations before application.
Modified vegetable oil adjuvants (1% v/v) improve rainfastness by 30-45% compared to non-adjuvanted applications. Silicone-based surfactants provide inconsistent improvement, and in some cases, may reduce residual activity against mite eggs.
Spirodiclofen insecticide exhibits favorable environmental characteristics compared to older acaricide chemistries:
Bee toxicity studies place spirodiclofen in WHO Class U (unlikely to present acute hazard) with acute oral LD50 >100 μg/bee. Its low water solubility minimizes aquatic exposure risks, with Daphnia magna EC50 = 0.19 mg/L at 48 hours. Current regulatory approvals include full registration under EPA (USA), EU Commission Regulation 540/2011, and registration in over 45 countries with no significant use restrictions anticipated based on current ecological risk assessments.
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