

Acephate, also known as Orthene, is a widely used organophosphate foliar insecticide designed to combat a variety of pests in agricultural and horticultural settings. This compound has been recognized as one of the 10 most important organophosphate insecticides since the 1990s and remains a critical tool for pest management today. Its mechanism of action involves inhibiting acetylcholinesterase (AChE), an enzyme essential for nerve signal transmission in insects. By disrupting this process, Acephate effectively controls pests while minimizing direct harm to non-target organisms, making it a preferred choice for many farmers and horticulturists.
Acephate is characterized by its broad-spectrum efficacy, systemic action, and compatibility with various application methods. Its chemical properties include a melting point of 93°C, a density of 1.35, and solubility in water, chloroform, and DMSO. These properties make it versatile for use in different formulations. The insecticide is available in multiple concentrations and forms, including technical concentrates, soluble powders, emulsifiable concentrates, and water-dispersible granules, catering to diverse agricultural needs.
| Property | Value |
|---|---|
| Melting Point | 93°C |
| Density | 1.35 |
| Vapor Pressure | 2.26 x 10⁻⁴ Pa (24°C) |
| Flash Point | 2°C |
| Storage Temperature | Approx. 4°C |
| Solubility | Chloroform: Soluble; DMSO: Soluble; Water: Soluble |
| pKa | 11.00±0.46 (Predicted) |
| Form | Solid |
| Color | White to yellow |
| Water Solubility | Readily soluble |
One of the primary advantages of Acephate is its dual mode of action as both a contact and systemic insecticide. This means it can kill pests on contact while also being absorbed into the plant's vascular system, providing long-lasting protection. Its moderate persistence ensures effective control without excessive environmental buildup. Additionally, Acephate's solubility in water allows for easy application through foliar sprays, making it a practical solution for large-scale agricultural operations.
Another significant benefit is its targeted efficacy against a wide range of pests, including aphids, leaf miners, caterpillars, and thrips. This versatility reduces the need for multiple pesticides, lowering costs and minimizing the risk of pest resistance. Furthermore, Acephate's formulation options, such as 97% TC technical concentrate and 40% EC emulsifiable concentrate, allow for customization based on specific crop requirements and environmental conditions.
Acephate is widely used in the control of sucking and chewing insects across various crops, including cotton, ornamentals, forestry, tobacco, fruits, vegetables, and other agricultural products. Its systemic activity makes it particularly effective against pests like the alfalfa looper, bean leafbeetle, and cabbage looper. Farmers and horticulturists often apply Acephate as a foliar spray, ensuring even coverage and rapid absorption by the plant.
The insecticide is also suitable for use in integrated pest management (IPM) programs, where it complements other control methods such as biological agents and cultural practices. Its compatibility with organic farming practices, when used according to guidelines, further enhances its appeal. For instance, Acephate's low toxicity to mammals and birds makes it a safer option compared to some other organophosphates, aligning with modern sustainability goals.
While Acephate is effective, it is classified under the GHS07 hazard symbol, indicating it is a warning for potential health risks. The Hazard statements H302+H312 highlight its toxicity if ingested or inhaled, and the Hazard Codes Xn (harmful) and F (flammable) emphasize the need for proper handling. Users must follow safety protocols, including wearing protective gear and adhering to storage guidelines (e.g., keeping it at approximately 4°C).
The HS Code 29299040 ensures that Acephate is regulated under international trade standards, promoting safe transportation and use. Compliance with these regulations is crucial for both manufacturers and end-users to mitigate risks associated with improper handling or disposal.

Hebei Dongfeng Chemical Technology Co., Ltd. (河北东沣化工科技有限公司) is a leading manufacturer of agrochemicals, specializing in the production of high-quality insecticides like Acephate. Established in 2005, the company has built a reputation for innovation, reliability, and adherence to international standards. With a focus on sustainable practices and cutting-edge research, Hebei Dongfeng supplies Acephate in multiple formulations, including 75% SP soluable powder and 98% TC technical concentrate, to meet the diverse needs of global markets.
The company's commitment to quality is reflected in its certifications, including ISO 9001 for quality management and compliance with the NIST standards for chemical safety. Hebei Dongfeng also invests in research to develop safer and more effective pest control solutions, ensuring that its products align with evolving agricultural demands and environmental regulations.
The safety and efficacy of Acephate are supported by guidelines from the National Institute of Standards and Technology (NIST), which provides critical data on chemical properties and hazard assessments. According to NIST, Acephate's chemical stability and solubility profiles are essential for ensuring its safe use in agricultural applications. Additionally, NIST's research on pesticide residues and environmental impact underscores the importance of proper storage and application practices to minimize ecological risks.
For further information on Acephate's regulatory compliance and safety data, refer to the NIST Chemical Safety Data and the product documentation provided by Hebei Dongfeng Chemical Technology Co., Ltd.
Acephate remains a vital tool in modern agriculture, offering effective pest control with a balance of systemic and contact action. Its technical specifications, broad application range, and availability in multiple formulations make it a versatile choice for farmers and horticulturists. While safety precautions are necessary, the insecticide's targeted efficacy and compatibility with sustainable practices ensure its continued relevance in the industry.
For more details about Acephate and its formulations, visit Hebei Dongfeng Chemical Technology Co., Ltd.. Explore the product page to learn how Acephate can enhance your pest management strategies.
